PRP can be placed in more than one way, and in more than one kind of tissue. The route is a clinical choice, and one method is not presented as superior to another.
Manual injection. A clinician uses a syringe to place PRP into selected sites. Most patients at the clinic choose manual injection performed by the physician. The injection pattern and approach are chosen for the anatomy and purpose of treatment.
Device-assisted injection. An injection device can deliver PRP across the planned treatment area for patients who prefer it; the clinic offers this using the Introfil device. Device-assisted delivery still involves injections and requires clinical judgement. The device and preparation must be compatible, and using a device does not establish that the PRP is more effective, painless or free of bruising.
PRP used with another procedure. Some protocols combine PRP with microneedling or other procedures. Applying PRP to treated skin is different from injecting it, and the evidence for one route should not be assumed to apply to another.
Injection into a joint, tendon or ligament. Where PRP is used for musculoskeletal problems rather than skin, it is placed under ultrasound guidance. This allows the joint, tendon or ligament and the nerves and vessels around it to be seen in real time, so the injection can be confirmed to reach the structure it is intended for. Musculoskeletal use is assessed separately from skin use, and evidence for one does not carry over to the other.