Technology

VAMP (PDRN Salmon DNA)

A topical polydeoxyribonucleotide (PDRN) formula applied immediately after microchannel-creating procedures to aid skin recovery and quality.

Want to understand VAMP (PDRN Salmon DNA)?

Anti-Aging Clinic can explain how this technology may fit into care, answer your questions, and help you explore the next step with a specialist.

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VAMP PDRN in Vancouver

Understanding VAMP (PDRN Salmon DNA).

VAMP is a topical regenerative formula built around PDRN (polydeoxyribonucleotide), a fragment of DNA derived from salmon. It's applied straight after in-clinic procedures that open tiny channels in the skin, such as microneedling, RF microneedling or laser, when the skin can take in a topical formula more readily. The aim is smoother recovery, better hydration and healthier-looking skin.

Our trained laser technicians provide microneedling, which may be combined with selected topical products, including VAMP (PDRN), exosome-based skincare formulations and other professional skin-supporting serums. Product selection is based on your skin and our clinical protocols.

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How does VAMP work?

PDRN is studied as a biological messenger, a molecule that prompts the skin's own repair activity. Research suggests it may stimulate fibroblasts, the cells that make collagen and elastin, and help calm inflammation. That's why it's used to support recovery and skin quality.

Applied after a microchannel procedure, the formula reaches beneath the surface during the short window when the skin barrier is open. Most published research looks at injected PDRN, and research on topical use is still developing, so VAMP is used to complement the procedure it follows.

What VAMP improves

VAMP is applied straight after barrier-opening procedures such as microneedling, RF microneedling and laser resurfacing, to support recovery, hydration, elasticity and overall skin quality.

Related concerns: dry, dull or dehydrated skin, uneven texture, acne scars, fine lines and crepey, thinning skin.

It's typically advised as part of a series spaced over several weeks, with periodic maintenance to help sustain your results.

Anti-Aging Medical & Laser Clinic

Curious where VAMP (PDRN Salmon DNA) may fit?

Anti-Aging Medical & Laser Clinic can help you explore this technology, related treatments, and connected concerns.

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Benefits of VAMP

  • Supports recovery after microneedling and laser treatments.
  • Hydration and skin quality that complement the collagen-building goals of your treatment.
  • Topical and gentle. Applied to the skin at the end of your procedure.
  • Progressive improvement over a planned series of sessions.

Individual results vary.

Plan Your Regenerative Facial Series →

Safety, side effects and considerations

VAMP is applied topically by our trained laser technicians straight after a procedure that opens tiny channels in the skin, under the medical direction of Dr. Gidon Frame. It's generally well tolerated, and most redness or sensitivity you notice comes from the procedure it follows.

Common and temporary

  • Redness, warmth and mild swelling from the microneedling or laser procedure
  • Dryness, tightness or light flaking as the skin recovers

Less common risks

  • Contact dermatitis: an itchy, red or bumpy rash from a reaction to an ingredient
  • Infection, because the microchannels leave the skin open for a short time
  • Temporary darkening of the skin after the procedure, which is more likely in deeper skin tones. Settings and aftercare are planned with your skin tone in mind.
  • Rarely, granuloma reactions: small, firm bumps that can appear when a topical product reaches deeper skin through open channels

When treatment may need to wait

  • A known allergy to fish or fish-derived ingredients (PDRN is sourced from salmon)
  • An active infection, cold sore or open wound in the treatment area
  • Previous reactions to skincare ingredients, which we'll review with you first
  • Pregnancy or breastfeeding, as a precaution

Normal healing or a reaction?

Normal recovery feels like a mild sunburn, with redness and tightness that ease steadily over the next few days. Contact the clinic on 604-261-9121 if redness or swelling is getting worse instead of better, or if you notice itching, a rash, pus, firm bumps, or pain beyond what you were told to expect.

Regulatory status. Injectable PDRN products aren't currently authorized by Health Canada. At our clinic, PDRN is used topically only, applied after treatments that create microchannels, in keeping with Canadian regulations.

This is not a complete list.

Conditions It May Help Address

Concerns connected to this technology.

The relationship between a technology and a concern depends on the treatment plan, patient assessment, and how the technology is being used.

Acne

Acne is a skin condition that can affect people of all ages and skin types. Our physicians assess what is happening in your skin and help you choose an appropriate medical treatment, maintenance and preventive plan as well as your at-home skincare.

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Neck Laxity and Neck Lines

Loose neck skin, horizontal creases, or visible muscle bands that can reduce definition of the neck and jawline.

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Not sure how VAMP (PDRN Salmon DNA) may fit?

Talk with Anti-Aging Clinic about your goals and the options that may be worth exploring.

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Anti-Aging Medical & Laser Clinic

Why patients choose our clinic for VAMP

  • Applied by our trained laser technicians, within our physician-led clinic under the medical direction of Dr. Gidon Frame.
  • Part of a complete plan. VAMP is paired with microneedling, Secret RF microneedling or laser treatments chosen for your skin.
  • Care between visits. Professional skincare from our online shop supports hydration and protects your results.
  • Physician-led care in Vancouver since 2003.

Your consultation. You'll meet our senior laser technicians or cosmetic health and skincare advisors, who look at your skin and goals and recommend the procedure and topical products that suit you. Cosmetic consultations are complimentary.

Start Your Skin Recovery Plan →

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FAQ

Questions about VAMP (PDRN Salmon DNA).

PDRN (polydeoxyribonucleotide) is a fragment of DNA whose structure is very similar to human DNA, which is thought to help skin cells recognize it. It's studied as a signal that may support the skin's natural repair, including collagen activity and calming inflammation. Salmon is a common, well-characterized source.

Injectable PDRN products aren't currently authorized by Health Canada. At our clinic, PDRN is used topically only, applied straight after treatments that create microchannels in the skin, so the formula can be absorbed after the procedure.

VAMP is usually advised as part of a series spaced over several weeks, with occasional maintenance afterward. The right number depends on your skin, your goals and the procedure it accompanies, and we'll map out a plan with you.

It isn't advised if you have a known allergy to fish-derived ingredients, an active infection or open wound in the treatment area, or, as a precaution, if you're pregnant or breastfeeding. Share your medical history with us so we can confirm it suits you.

Reviews

What patients say about the clinic experience.

Reviews help show the human side of care, from the first consultation to comfort, communication, treatment planning, and follow-up.

Medical Review

Reviewed for clinical accuracy.

Medically reviewed by Dr. Gidon Frame, Medical Director, Anti-Aging Medical & Laser Clinic (CPSBC).
Last medically reviewed: August 2026.
Evidence reviewed: clinical practice guidelines, systematic reviews and peer-reviewed medical literature.

AuthorDr. Gidon Frame
Medical ReviewerDr. Gidon Frame
Last ReviewedSeptember 2026
Anti-Aging Medical & Laser Clinic

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Why Anti-Aging Medical & Laser Clinic?

  • A medical clinic with physicians and experienced medical-aesthetic providers on the team.
  • Science-informed assessment, treatment planning, and realistic expectations.
  • Laser, injectables, skin, body, hair, wellness, and medical services available in one clinic.
  • Complimentary aesthetic consultations are available for appropriate cosmetic and laser services.
  • Personalized skincare and product consultations based on your goals and routine.
  • Home-care guidance to support your skin between in-clinic appointments.
  • Professional skincare products available through the Anti-Aging Vancouver shop.
  • Clear guidance on treatment options, preparation, downtime, aftercare, and next steps.
  • Ongoing follow-up so your plan can evolve as your needs and goals change.